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Age:	≤ 60 > 60
Stage:	I or II III or IV
LDH:	Normal Elevated
# Extranodal Site:	0 or 1 > 1
Performance Status (ECOG):	< 2 ≥ 2
B Symptoms:	Absent Present
Testicular Involvement:	Absent Present
CNS Involvement:	Absent Present
Response to Initial Therapy:	Complete Response Partial Response No Response
MYC Expression:	Not High High
BCL2 Expression:	Not High High
ABC/GCB Classification:	ABC GCB Unclassified

Available Genes ACTB ANKRD17 ARID1A ARID1B ARID5B ATM ATR B2M BCL10 BCL2 BCL6 BCL7A BIRC6 BRAF BRINP3 BTBD3 BTG1 BTG2 BTK CARD11 CASP8 CBLB CCND3 CD22 CD58 CD70 CD79B CD83 CDC73 CDKN2A CHD1 CHD8 CHST2 CIITA CREBBP CXCR4 DCAF6 DDX10 DDX3X DICER1 DNMT3A DUSP2 EBF1 EP300 ETS1 ETV6 EZH2 FAS FBXW7 FOXO1 FOXP1 FUBP1 GNA13 GNAI2 GNAS GOLGA5 HIST1H1E HIST1H2BC HNRNPD HNRNPU HRAS IKBKB IKZF3 IL16 INO80 IRF4 IRF8 JAK1 JAK3 JUNB KCMF1 KLHL14 KLHL6 KMT2C KMT2D KRAS LIN54 MAGT1 MAP2K1 MAP4K4 MARK1 MCL1 MECOM MEF2B MET MGA MSH2 MSH6 MTOR MYB MYC MYD88 NCOR1 NF1 NFKB2 NFKBIA NFKBIE NOTCH2 PAX5 PHF6 PIK3CD PIK3R1 PIM1 PIM2 POU2F2 PRDM1 PTEN PTPN6 PTPRK RARA RB1 RHOA RRAGC RUNX1 S1PR2 SETD1B SETD2 SETD5 SF3B1 SGK1 SMARCA4 SOCS1 SPEN STAT3 STAT5B STAT6 SYK TAF1 TBL1XR1 TCL1A TET2 TGFBR2 TIPARP TMEM30A TMSB4X TNFAIP3 TNFRSF14 TOX TP53 UBE2A UBR5 WAC XPO1 YY1 ZBTB7A ZEB2 ZFAT ZFX ZNF292 ZNF608

Selected Genes

Data Set	Sample Size	3-Year Survival Rate	0.95 Confidence Interval
Affected Patients	4	25.00 %	[0.89%, 66.54%]
Remaining Patients	348	74.87 %	[69.64%, 79.33%]
p-value: 0.005

Age: ≤ 60 LDH: Elevated B Symptoms: Present Testicular Involvement: Absent CNS Involvement: Present